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008 011011s2002 njua ob 001 0 eng c
020 _a0896038238 (alk. paper)
020 _a9780896038233 (alk. paper)
020 _a9781592592715 (eISBN)
020 _a1592592716 (eISBN)
035 _a(OCoLC)170845101
035 _a(OCoLC)81290779
035 _a(OCoLC)320967460
035 _a(OCoLC)658115860
040 _aCOO
_cALUPE UNIVERSITY
_dN$T
_dYDXCP
_dSCB
_dCUV
_dCASUM
_dCNTRU
_dGW5XE
_dPUL
_dOCLCE
_dIDEBK
042 _apcc
049 _aMYGG
050 1 4 _aQR201.M3
_bM337 2002
060 4 _aW1 ME9616JM
_bv.72 2002
060 4 _aWC 25
_bM237 2002
082 0 4 _a616.9/362/0072
_221
084 _a44.44
_2bcl
245 0 0 _aMalaria methods and protocols
_h[electronic resource] /
_cedited by Denise L. Doolan.
260 _aTotowa, N.J. :
_bHumana Press,
_cc2002.
300 _axv, 631 p. :
_bill. ;
_c27 cm.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
490 1 _aMethods in molecular medicine ;
_v72
504 _aIncludes bibliographical references and index.
505 0 _aVector incrimination and entomological inoculation rates -- Epidemiological measures of risk of malaria -- Maintenance of the Plasmodium berghei life cycle -- Mouse models for pre-erythrocytic-stage malaria -- Mouse models for erythrocytic-stage malaria -- Nonhuman primate models. I. Nonhuman primate host-parasite combinations -- Nonhuman primate models. II. Infection of Saimiri and Aotus monkeys with Plasmodium vivax -- Vector analysis -- Genotyping of Plasmodium spp. Nested PCR -- Genotyping of Plasmodium falciparum. PCR-RFLP analysis -- Microsatellite analysis in Plasmodium falciparum -- Quantitation of liver-stage parasites by automated TaqMan real-time PCR -- Quantitation of liver-stage parasites by competitive RT-PCR -- Extraction and purification of Plasmodium total RNA -- Extraction and purification of Plasmodium parasite DNA -- Southern blotting of parasite DNA -- SDS-PAGE and western blotting of Plasmodium falciparum proteins -- Nested PCR analysis of Plasmodium parasites -- RFLP analysis -- Analysis of gene expression by RT-PCR -- In situ detection of RNA in blood- and mosquito-stage malaria parasites -- Purification of chromosomes from Plasmodium falciparum -- Construction of genomic libraries from the DNA of Plasmodium species -- Construction of a gene library with mung bean nuclease-treated genomic DNA -- Construction of Plasmodium falciparum lambda cDNA libraries -- Production of stage-specific Plasmodium falciparum cDNA libraries using subtractive hybridization -- Construction and screening of YAC libraries -- Episomal transformation of Plasmodium berghei -- Gene targeting in Plasmodium berghei -- Peptide vaccination -- DNA vaccination -- Assessing antigen-specific CD8+ and CD4+ T-cell responses in mice after immunization with recombinant viruses -- Assessing CD4+ helper T-lymphocyte responses by lymphoproliferation -- Limiting dilution analysis of antigen-specific CD4+ T-cell responses in mice -- Cell trafficking. Malaria blood-stage parasite-specific CD4+ T cells after adoptive transfer into mice -- Assessing antigen-specific proliferation and cytokine responses using flow cytometry -- Cytokine analysis by intracellular staining -- Assessment of antigen-specific CTL- and CD8(+)-dependent IFN-gamma responses in mice -- Assessing antigen-specific CD8+ CTL responses in humans -- Human antibody subclass ELISA -- Systemic nitric oxide production in human malaria. I. Analysis of NO metabolites in biological fluids -- Systemic nitric oxide production in human malaria. II. Analysis of mononuclear cell nitric oxide synthase type 2 antigen expression -- In vitro culture of Plasmodium parasites -- Automated synchronization of Plasmodium falciparum parasites by culture in a temperature-cycling incubator -- Hepatic portal branch inoculation -- Hepatocyte perfusion, isolation, and culture -- Inhibition of sporozoite invasion. The double-staining assay -- Inhibition of liver-stage development assay -- T-cell mediated inhibition of liver-stage development assay -- Antibody-dependent cellular inhibition assay -- Erythrocytic malaria growth or invasion inhibition assays with emphasis on suspension culture GIA -- Analysis of CSA-binding parasites and antiadhesion antibodies -- Analysis of the adhesive properties of Plasmodium falciparum-infected red blood cells under conditions of flow -- Preparation of adhesive targets for flow-based cytoadhesion assays -- Triton X-114 phase partitioning for antigen characterization -- Immunoprecipitation for antigen localization -- Field trials.
506 _aAccess is restricted to subscribing institutions.
530 _aAlso issued in print.
533 _aElectronic reproduction.
_nMode of access: World Wide Web.
_nSystem requirements: Web browser.
_nAccess may be restricted to users at subscribing institutions.
650 0 _aMalaria
_vLaboratory manuals.
655 7 _aLaboratory manuals.
_2lcgft
655 7 _aFulltext
_2local
655 7 _aIllustration
_2local
655 7 _aIndex not Present
_2local
655 7 _aInternet Resource
_2local
655 7 _aLaboratory Manual
_2local
700 1 _aDoolan, Denise L.
776 0 8 _iPrint version:
_tMalaria methods and protocols.
_dTotowa, N.J. : Humana Press, c2002
_z0896038238
_w(DLC) 2001051656
_w(OCoLC)48162854
830 0 _aMethods in molecular medicine ;
_v72.
856 4 0 _uhttp://dx.doi.org/10.1385/1592592716
910 _aMARCIVEAUT
910 _aMARCIVEAUT
910 _aMARCIVEAUT
910 _aMARCIVEAUT
910 _aBatchload
910 _aMARCIVEAUT
910 _aMARCIVEAUT
910 _aBatchload
910 _aBatchload
910 _aMARCIVEAUT
942 _2lcc
_cBK
_nPW
946 _mSpringerProtocols
949 1 _1MIT Access Only
_an-mit
_bNET
_h**See URL(s)
_o8
_x02